Acute larvicidal toxicity of five essential oils (Pinus nigra, Hyssopus officinalis, Satureja montana, Aloysia citrodora and Pelargonium graveolens) against the filariasis vector Culex quinquefasciatus: Synergistic and antagonistic effects.
Identifieur interne : 000806 ( Main/Exploration ); précédent : 000805; suivant : 000807Acute larvicidal toxicity of five essential oils (Pinus nigra, Hyssopus officinalis, Satureja montana, Aloysia citrodora and Pelargonium graveolens) against the filariasis vector Culex quinquefasciatus: Synergistic and antagonistic effects.
Auteurs : Giovanni Benelli [Italie] ; Roman Pavela [République tchèque] ; Angelo Canale [Italie] ; Kevin Cianfaglione [Italie] ; Giampiero Ciaschetti [Italie] ; Fabio Conti [Italie] ; Marcello Nicoletti [Italie] ; Sengottayan Senthil-Nathan [Inde] ; Heinz Mehlhorn [Allemagne] ; Filippo Maggi [Italie]Source :
- Parasitology international [ 1873-0329 ] ; 2017.
Descripteurs français
- KwdFr :
- Animaux, Antagonisme des médicaments, Chromatographie gazeuse-spectrométrie de masse, Culex (), Encéphalite de Saint-Louis (), Encéphalite de Saint-Louis (transmission), Feuilles de plante (), Filariose lymphatique (), Filariose lymphatique (transmission), Fièvre à virus West Nile (), Fièvre à virus West Nile (transmission), Huile essentielle (), Huile essentielle (pharmacologie), Huiles végétales (), Huiles végétales (pharmacologie), Hyssopus (), Insecticides (), Insecticides (pharmacologie), Larve (), Moustiques vecteurs (), Pelargonium (), Pinus (), Satureja (), Synergie des médicaments, Verbenaceae ().
- MESH :
- pharmacologie : Huile essentielle, Huiles végétales, Insecticides.
- Animaux, Antagonisme des médicaments, Chromatographie gazeuse-spectrométrie de masse, Culex, Encéphalite de Saint-Louis, Feuilles de plante, Filariose lymphatique, Fièvre à virus West Nile, Huile essentielle, Huiles végétales, Hyssopus, Insecticides, Larve, Moustiques vecteurs, Pelargonium, Pinus, Satureja, Synergie des médicaments, Verbenaceae.
English descriptors
- KwdEn :
- Animals, Culex (drug effects), Drug Antagonism, Drug Synergism, Elephantiasis, Filarial (prevention & control), Elephantiasis, Filarial (transmission), Encephalitis, St. Louis (prevention & control), Encephalitis, St. Louis (transmission), Gas Chromatography-Mass Spectrometry, Hyssopus Plant (chemistry), Insecticides (chemistry), Insecticides (pharmacology), Larva (drug effects), Mosquito Vectors (drug effects), Oils, Volatile (chemistry), Oils, Volatile (pharmacology), Pelargonium (chemistry), Pinus (chemistry), Plant Leaves (chemistry), Plant Oils (chemistry), Plant Oils (pharmacology), Satureja (chemistry), Verbenaceae (chemistry), West Nile Fever (prevention & control), West Nile Fever (transmission).
- MESH :
- chemical , chemistry : Insecticides, Oils, Volatile, Plant Oils.
- chemistry : Hyssopus Plant, Pelargonium, Pinus, Plant Leaves, Satureja, Verbenaceae.
- drug effects : Culex, Larva, Mosquito Vectors.
- chemical , pharmacology : Insecticides, Oils, Volatile, Plant Oils.
- prevention & control : Elephantiasis, Filarial, Encephalitis, St. Louis, West Nile Fever.
- transmission : Elephantiasis, Filarial, Encephalitis, St. Louis, West Nile Fever.
- Animals, Drug Antagonism, Drug Synergism, Gas Chromatography-Mass Spectrometry.
Abstract
Mosquito vector control is facing a number of important and timely challenges, mainly due to the rapid development of pesticide resistance and environmental concerns. In this scenario, screening of botanical resources for their mosquitocidal activity may offer effective and eco-friendly tools against Culicidae vectors. Culex quinquefasciatus Say (Diptera: Culicidae) is a vector of lymphatic filariasis and of dangerous arboviral diseases, such as West Nile and St. Louis encephalitis. In this study, the chemical composition of five essential oils obtained from different plants, namely Pinus nigra J.F. Arnold var. italica (Pinaceae), Hyssopus officinalis L. subsp. aristatus (Lamiaceae), Satureja montana L. subsp. montana (Lamiaceae), Aloysia citriodora Palau (Verbenaceae) and Pelargonium graveolens L'Hér (Geraniaceae), was investigated by GC-MS analysis. Furthermore, it was evaluated their acute toxicity on larvae of C. quinquefasciatus. Then, the most effective oils were selected, in order to focus on the potential synergistic and antagonistic effects, testing them in binary mixtures on C. quinquefasciatus larvae. Results showed that the higher effectiveness was obtained by S. montana subsp. montana essential oil (LC50=25.6μL·L(-1)), followed by P. nigra var. italica (LC50=49.8μL·L(-1)) and A. citriodora (LC50=65.6μL·L(-1)), while the other essential oils showed LC50 values higher than 90μL·L(-1). The larvicidal effectiveness can be enhanced by preparing simple binary mixtures of essential oils, such as S. montana+A. citriodora (ratio 1:1), which showed higher larvicidal toxicity (LC50=18.3μL·L(-1)). On the other hand, testing S. montana+P. nigra (1:1) an antagonistic effect was detected, leading to a LC50 (72.5μL·L(-1)) higher than the LC50 values calculated for the two oils tested separately. Overall, our results add useful knowledge to allow the employ of synergistic essential oil blends as effective, cheap and eco-friendly mosquito larvicides.
DOI: 10.1016/j.parint.2017.01.012
PubMed: 28110082
Affiliations:
- Allemagne, Inde, Italie, République tchèque
- District de Düsseldorf, Latium, Rhénanie-du-Nord-Westphalie, Région Bretagne, Toscane
- Brest, Düsseldorf, Pise, Rome
- Université de Bretagne Occidentale, Université de Pise
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Le document en format XML
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type="city">Rome</settlement><region nuts="2">Latium</region></placeName></affiliation></author><author><name sortKey="Senthil Nathan, Sengottayan" sort="Senthil Nathan, Sengottayan" uniqKey="Senthil Nathan S" first="Sengottayan" last="Senthil-Nathan">Sengottayan Senthil-Nathan</name><affiliation wicri:level="1"><nlm:affiliation>Division of Biopesticides and Environmental Toxicology, Sri Paramakalyani Centre for Excellence in Environmental Sciences, Manonmaniam Sundaranar University, Alwarkurichi, 627 412 Tirunelveli, Tamil Nadu, India.</nlm:affiliation><country xml:lang="fr">Inde</country><wicri:regionArea>Division of Biopesticides and Environmental Toxicology, Sri Paramakalyani Centre for Excellence in Environmental Sciences, Manonmaniam Sundaranar University, Alwarkurichi, 627 412 Tirunelveli, Tamil Nadu</wicri:regionArea><wicri:noRegion>Tamil Nadu</wicri:noRegion></affiliation></author><author><name sortKey="Mehlhorn, Heinz" sort="Mehlhorn, Heinz" uniqKey="Mehlhorn H" first="Heinz" last="Mehlhorn">Heinz Mehlhorn</name><affiliation wicri:level="3"><nlm:affiliation>Department of Parasitology, Heinrich Heine University, Düsseldorf, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Parasitology, Heinrich Heine University, Düsseldorf</wicri:regionArea><placeName><region type="land" nuts="1">Rhénanie-du-Nord-Westphalie</region><region type="district" nuts="2">District de Düsseldorf</region><settlement type="city">Düsseldorf</settlement></placeName></affiliation></author><author><name sortKey="Maggi, Filippo" sort="Maggi, Filippo" uniqKey="Maggi F" first="Filippo" last="Maggi">Filippo Maggi</name><affiliation wicri:level="1"><nlm:affiliation>School of Pharmacy, University of Camerino, Camerino, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>School of Pharmacy, University of Camerino, 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Electronic address: benelli.giovanni@gmail.com.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Agriculture, Food and Environment, University of Pisa, via del Borghetto 80, 56124 Pisa</wicri:regionArea><placeName><settlement type="city">Pise</settlement><region nuts="2">Toscane</region><settlement type="city">Pise</settlement></placeName><orgName type="university">Université de Pise</orgName></affiliation></author><author><name sortKey="Pavela, Roman" sort="Pavela, Roman" uniqKey="Pavela R" first="Roman" last="Pavela">Roman Pavela</name><affiliation wicri:level="1"><nlm:affiliation>Crop Research Institute, Drnovska 507, 161 06 Prague 6, Czech Republic.</nlm:affiliation><country xml:lang="fr">République tchèque</country><wicri:regionArea>Crop Research Institute, Drnovska 507, 161 06 Prague 6</wicri:regionArea><wicri:noRegion>161 06 Prague 6</wicri:noRegion></affiliation></author><author><name sortKey="Canale, Angelo" sort="Canale, Angelo" uniqKey="Canale A" first="Angelo" last="Canale">Angelo Canale</name><affiliation wicri:level="4"><nlm:affiliation>Department of Agriculture, Food and Environment, University of Pisa, via del Borghetto 80, 56124 Pisa, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Agriculture, Food and Environment, University of Pisa, via del Borghetto 80, 56124 Pisa</wicri:regionArea><placeName><settlement type="city">Pise</settlement><region nuts="2">Toscane</region><settlement type="city">Pise</settlement></placeName><orgName type="university">Université de Pise</orgName></affiliation></author><author><name sortKey="Cianfaglione, Kevin" sort="Cianfaglione, Kevin" uniqKey="Cianfaglione K" first="Kevin" last="Cianfaglione">Kevin Cianfaglione</name><affiliation wicri:level="4"><nlm:affiliation>Géoarchitecture, UFR Sciences & Techniques, Université de Bretagne Occidentale, Brest, France; School of Biosciences and Veterinary Medicine, University of Camerino, Camerino, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Géoarchitecture, UFR Sciences & Techniques, Université de Bretagne Occidentale, Brest, France; School of Biosciences and Veterinary Medicine, University of Camerino, Camerino</wicri:regionArea><orgName type="university">Université de Bretagne Occidentale</orgName><placeName><settlement type="city">Brest</settlement><region type="region" nuts="2">Région Bretagne</region></placeName></affiliation></author><author><name sortKey="Ciaschetti, Giampiero" sort="Ciaschetti, Giampiero" uniqKey="Ciaschetti G" first="Giampiero" last="Ciaschetti">Giampiero Ciaschetti</name><affiliation wicri:level="1"><nlm:affiliation>Majella National Park, Sulmona, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Majella National Park, Sulmona</wicri:regionArea><wicri:noRegion>Sulmona</wicri:noRegion></affiliation></author><author><name sortKey="Conti, Fabio" sort="Conti, Fabio" uniqKey="Conti F" first="Fabio" last="Conti">Fabio Conti</name><affiliation wicri:level="1"><nlm:affiliation>School of Bioscience and Veterinary Medicine, University of Camerino, Centro Ricerche Floristiche dell'Appennino, San Colombo, Barisciano, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>School of Bioscience and Veterinary Medicine, University of Camerino, Centro Ricerche Floristiche dell'Appennino, San Colombo, Barisciano</wicri:regionArea><wicri:noRegion>Barisciano</wicri:noRegion></affiliation></author><author><name sortKey="Nicoletti, Marcello" sort="Nicoletti, Marcello" uniqKey="Nicoletti M" first="Marcello" last="Nicoletti">Marcello Nicoletti</name><affiliation wicri:level="3"><nlm:affiliation>Department of Environmental Biology, Sapienza University, Rome, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Environmental Biology, Sapienza University, Rome</wicri:regionArea><placeName><settlement type="city">Rome</settlement><region nuts="2">Latium</region></placeName></affiliation></author><author><name sortKey="Senthil Nathan, Sengottayan" sort="Senthil Nathan, Sengottayan" uniqKey="Senthil Nathan S" first="Sengottayan" last="Senthil-Nathan">Sengottayan Senthil-Nathan</name><affiliation wicri:level="1"><nlm:affiliation>Division of Biopesticides and Environmental Toxicology, Sri Paramakalyani Centre for Excellence in Environmental Sciences, Manonmaniam Sundaranar University, Alwarkurichi, 627 412 Tirunelveli, Tamil Nadu, India.</nlm:affiliation><country xml:lang="fr">Inde</country><wicri:regionArea>Division of Biopesticides and Environmental Toxicology, Sri Paramakalyani Centre for Excellence in Environmental Sciences, Manonmaniam Sundaranar University, Alwarkurichi, 627 412 Tirunelveli, Tamil Nadu</wicri:regionArea><wicri:noRegion>Tamil Nadu</wicri:noRegion></affiliation></author><author><name sortKey="Mehlhorn, Heinz" sort="Mehlhorn, Heinz" uniqKey="Mehlhorn H" first="Heinz" last="Mehlhorn">Heinz Mehlhorn</name><affiliation wicri:level="3"><nlm:affiliation>Department of Parasitology, Heinrich Heine University, Düsseldorf, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Parasitology, Heinrich Heine University, Düsseldorf</wicri:regionArea><placeName><region type="land" nuts="1">Rhénanie-du-Nord-Westphalie</region><region type="district" nuts="2">District de Düsseldorf</region><settlement type="city">Düsseldorf</settlement></placeName></affiliation></author><author><name sortKey="Maggi, Filippo" sort="Maggi, Filippo" uniqKey="Maggi F" first="Filippo" last="Maggi">Filippo Maggi</name><affiliation wicri:level="1"><nlm:affiliation>School of Pharmacy, University of Camerino, Camerino, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>School of Pharmacy, University of Camerino, Camerino</wicri:regionArea><wicri:noRegion>Camerino</wicri:noRegion></affiliation></author></analytic><series><title level="j">Parasitology international</title><idno type="eISSN">1873-0329</idno><imprint><date when="2017" type="published">2017</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Animals</term><term>Culex (drug effects)</term><term>Drug Antagonism</term><term>Drug Synergism</term><term>Elephantiasis, Filarial (prevention & control)</term><term>Elephantiasis, Filarial (transmission)</term><term>Encephalitis, St. Louis (prevention & control)</term><term>Encephalitis, St. Louis (transmission)</term><term>Gas Chromatography-Mass Spectrometry</term><term>Hyssopus Plant (chemistry)</term><term>Insecticides (chemistry)</term><term>Insecticides (pharmacology)</term><term>Larva (drug effects)</term><term>Mosquito Vectors (drug effects)</term><term>Oils, Volatile (chemistry)</term><term>Oils, Volatile (pharmacology)</term><term>Pelargonium (chemistry)</term><term>Pinus (chemistry)</term><term>Plant Leaves (chemistry)</term><term>Plant Oils (chemistry)</term><term>Plant Oils (pharmacology)</term><term>Satureja (chemistry)</term><term>Verbenaceae (chemistry)</term><term>West Nile Fever (prevention & control)</term><term>West Nile Fever (transmission)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Animaux</term><term>Antagonisme des médicaments</term><term>Chromatographie gazeuse-spectrométrie de masse</term><term>Culex ()</term><term>Encéphalite de Saint-Louis ()</term><term>Encéphalite de Saint-Louis (transmission)</term><term>Feuilles de plante ()</term><term>Filariose lymphatique ()</term><term>Filariose lymphatique (transmission)</term><term>Fièvre à virus West Nile ()</term><term>Fièvre à virus West Nile (transmission)</term><term>Huile essentielle ()</term><term>Huile essentielle (pharmacologie)</term><term>Huiles végétales ()</term><term>Huiles végétales (pharmacologie)</term><term>Hyssopus ()</term><term>Insecticides ()</term><term>Insecticides (pharmacologie)</term><term>Larve ()</term><term>Moustiques vecteurs ()</term><term>Pelargonium ()</term><term>Pinus ()</term><term>Satureja ()</term><term>Synergie des médicaments</term><term>Verbenaceae ()</term></keywords><keywords scheme="MESH" type="chemical" qualifier="chemistry" xml:lang="en"><term>Insecticides</term><term>Oils, Volatile</term><term>Plant Oils</term></keywords><keywords scheme="MESH" qualifier="chemistry" xml:lang="en"><term>Hyssopus Plant</term><term>Pelargonium</term><term>Pinus</term><term>Plant Leaves</term><term>Satureja</term><term>Verbenaceae</term></keywords><keywords scheme="MESH" qualifier="drug effects" xml:lang="en"><term>Culex</term><term>Larva</term><term>Mosquito Vectors</term></keywords><keywords scheme="MESH" qualifier="pharmacologie" xml:lang="fr"><term>Huile essentielle</term><term>Huiles végétales</term><term>Insecticides</term></keywords><keywords scheme="MESH" type="chemical" qualifier="pharmacology" xml:lang="en"><term>Insecticides</term><term>Oils, Volatile</term><term>Plant Oils</term></keywords><keywords scheme="MESH" qualifier="prevention & control" xml:lang="en"><term>Elephantiasis, Filarial</term><term>Encephalitis, St. Louis</term><term>West Nile Fever</term></keywords><keywords scheme="MESH" qualifier="transmission" xml:lang="en"><term>Elephantiasis, Filarial</term><term>Encephalitis, St. Louis</term><term>West Nile Fever</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Animals</term><term>Drug Antagonism</term><term>Drug Synergism</term><term>Gas Chromatography-Mass Spectrometry</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Animaux</term><term>Antagonisme des médicaments</term><term>Chromatographie gazeuse-spectrométrie de masse</term><term>Culex</term><term>Encéphalite de Saint-Louis</term><term>Feuilles de plante</term><term>Filariose lymphatique</term><term>Fièvre à virus West Nile</term><term>Huile essentielle</term><term>Huiles végétales</term><term>Hyssopus</term><term>Insecticides</term><term>Larve</term><term>Moustiques vecteurs</term><term>Pelargonium</term><term>Pinus</term><term>Satureja</term><term>Synergie des médicaments</term><term>Verbenaceae</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Mosquito vector control is facing a number of important and timely challenges, mainly due to the rapid development of pesticide resistance and environmental concerns. In this scenario, screening of botanical resources for their mosquitocidal activity may offer effective and eco-friendly tools against Culicidae vectors. Culex quinquefasciatus Say (Diptera: Culicidae) is a vector of lymphatic filariasis and of dangerous arboviral diseases, such as West Nile and St. Louis encephalitis. In this study, the chemical composition of five essential oils obtained from different plants, namely Pinus nigra J.F. Arnold var. italica (Pinaceae), Hyssopus officinalis L. subsp. aristatus (Lamiaceae), Satureja montana L. subsp. montana (Lamiaceae), Aloysia citriodora Palau (Verbenaceae) and Pelargonium graveolens L'Hér (Geraniaceae), was investigated by GC-MS analysis. Furthermore, it was evaluated their acute toxicity on larvae of C. quinquefasciatus. Then, the most effective oils were selected, in order to focus on the potential synergistic and antagonistic effects, testing them in binary mixtures on C. quinquefasciatus larvae. Results showed that the higher effectiveness was obtained by S. montana subsp. montana essential oil (LC50=25.6μL·L(-1)), followed by P. nigra var. italica (LC50=49.8μL·L(-1)) and A. citriodora (LC50=65.6μL·L(-1)), while the other essential oils showed LC50 values higher than 90μL·L(-1). The larvicidal effectiveness can be enhanced by preparing simple binary mixtures of essential oils, such as S. montana+A. citriodora (ratio 1:1), which showed higher larvicidal toxicity (LC50=18.3μL·L(-1)). On the other hand, testing S. montana+P. nigra (1:1) an antagonistic effect was detected, leading to a LC50 (72.5μL·L(-1)) higher than the LC50 values calculated for the two oils tested separately. Overall, our results add useful knowledge to allow the employ of synergistic essential oil blends as effective, cheap and eco-friendly mosquito larvicides.</div></front></TEI><affiliations><list><country><li>Allemagne</li><li>Inde</li><li>Italie</li><li>République tchèque</li></country><region><li>District de Düsseldorf</li><li>Latium</li><li>Rhénanie-du-Nord-Westphalie</li><li>Région Bretagne</li><li>Toscane</li></region><settlement><li>Brest</li><li>Düsseldorf</li><li>Pise</li><li>Rome</li></settlement><orgName><li>Université de Bretagne Occidentale</li><li>Université de Pise</li></orgName></list><tree><country name="Italie"><region name="Toscane"><name sortKey="Benelli, Giovanni" sort="Benelli, Giovanni" uniqKey="Benelli G" first="Giovanni" last="Benelli">Giovanni Benelli</name></region><name sortKey="Canale, Angelo" sort="Canale, Angelo" uniqKey="Canale A" first="Angelo" last="Canale">Angelo Canale</name><name sortKey="Cianfaglione, Kevin" sort="Cianfaglione, Kevin" uniqKey="Cianfaglione K" first="Kevin" last="Cianfaglione">Kevin Cianfaglione</name><name sortKey="Ciaschetti, Giampiero" sort="Ciaschetti, Giampiero" uniqKey="Ciaschetti G" first="Giampiero" last="Ciaschetti">Giampiero Ciaschetti</name><name sortKey="Conti, Fabio" sort="Conti, Fabio" uniqKey="Conti F" first="Fabio" last="Conti">Fabio Conti</name><name sortKey="Maggi, Filippo" sort="Maggi, Filippo" uniqKey="Maggi F" first="Filippo" last="Maggi">Filippo Maggi</name><name sortKey="Nicoletti, Marcello" sort="Nicoletti, Marcello" uniqKey="Nicoletti M" first="Marcello" last="Nicoletti">Marcello Nicoletti</name></country><country name="République tchèque"><noRegion><name sortKey="Pavela, Roman" sort="Pavela, Roman" uniqKey="Pavela R" first="Roman" last="Pavela">Roman Pavela</name></noRegion></country><country name="Inde"><noRegion><name sortKey="Senthil Nathan, Sengottayan" sort="Senthil Nathan, Sengottayan" uniqKey="Senthil Nathan S" first="Sengottayan" last="Senthil-Nathan">Sengottayan Senthil-Nathan</name></noRegion></country><country name="Allemagne"><region name="Rhénanie-du-Nord-Westphalie"><name sortKey="Mehlhorn, Heinz" sort="Mehlhorn, Heinz" uniqKey="Mehlhorn H" first="Heinz" last="Mehlhorn">Heinz Mehlhorn</name></region></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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|texte= Acute larvicidal toxicity of five essential oils (Pinus nigra, Hyssopus officinalis, Satureja montana, Aloysia citrodora and Pelargonium graveolens) against the filariasis vector Culex quinquefasciatus: Synergistic and antagonistic effects.
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